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In rare instances, numerous Rosenthal fibres have been found at autopsy in patients who have suffered protracted debilitating systemic illnesses, some with associated brain stem signs, and in very rare instances in patients with no apparent neurological abnormality. The term Rosenthal fibre encephalopathy is used to distinguish these cases from those of Alexanders disease. We report the first case of Rosenthal fibre encephalopathy in a young man with AIDS, and review the literature. |
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